Function of mitochondria >> Respiration >> Mitochondrial parameters >> maximal respiration

Related Drugs/Compounds

Compound	Dose	Time	Species	Model	Method	Action	Result	Positive criterion	Reference
tacrolimus	50 µg/ml	12hr		INS-1 cells	XF24 Extracellular Flux Analyzer	decrease	Positive		322
xanthone	20 µM		zebrafish		XFe24 Extracellular Flux Analyzer	decrease	Positive		86
2,4-dinitrophenol	0.5 μM / 24 hpf		zebrafish		XFe24 Extracellular Flux Analyzer	decrease	Positive		90
triclosan	30 μM		zebrafish		XFe24 Extracellular Flux Analyzer	decrease	Positive		89
quercetin	1 µg/l		zebrafish		XFe24 Extracellular Flux Analyzer	decrease	Positive		91
fluoranthene	100 µg/l		zebrafish		XFe24 Extracellular Flux Analyzer	decrease	Positive		85
diquat	100 μM		zebrafish		XFe24 Extracellular Flux Analyzer	decrease	Positive		92
Phenanthrenequinone	2 µM		zebrafish		XFe24 Extracellular Flux Analyzer	decrease	Positive		86
Metformin	2mM	30 minutes	mouse; C57BL/6J	isolated skeletal muscle mitochondria	Measurement of Oxygen level; incubated in complex I substrate; added FCCP (1.5 μM)	decrease	Positive	p < 0.05	172
benz(a)anthracene-7,12-dione	5 µM		zebrafish		XFe24 Extracellular Flux Analyzer	decrease	Positive		86
1,9-benz-10-anthrone	10 µM		zebrafish		XFe24 Extracellular Flux Analyzer	decrease	Positive		86