F021203 | ATP level

Compound Dose Time Species Model Method Action Result Positive criterion Reference
Amitriptyline Positive 197
Desipramine Positive 197
Troglitazone >25 µM 1 and 2 hr HepG2 cells Cellular ATP concentrations were measured with a ATP Bioluminescent Somatic Cell Assay Kit decrease Positive 332
Troglitazone human hepatocytes ATP bioluminescence assay decrease Positive 226
Diazepam 150μg/ml 2hr PE cells luciferin-luciferase method decrease Positive 293