F04 | Movement of mitochondria


Movement of mitochondria

Compound Dose Time Species Model Method Action Result Positive criterion Reference
8-OH-DPAT 10nM 2h rat Hippocampal Neurons time-lapse imaging experiments increase Positive 215
1,3-Dihydro-1-(1-(4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one 5 μM 30min rat Hippocampal Neurons time-lapse imaging experiments decrease Positive 215
alpha-4-Dibromoacetophenone 0.05 μM 2h rat Hippocampal Neurons time-lapse imaging experiments increase Positive paired t-test; p < 0.02 215
bromocriptine 5 µM 2h rat Hippocampal Neurons time-lapse imaging experiments decrease Positive 216
SKF38393 33 µM 2h rat Hippocampal Neurons time-lapse imaging experiments increase Positive paired t-test; p < 0.02 216
Haloperidol 10 µM 2h rat Hippocampal Neurons time-lapse imaging experiments increase Positive 216
SCH23390 55 µM 2h rat Hippocampal Neurons time-lapse imaging experiments decrease Positive 216
CCCP 1mM Neurons derived from the dorsal root ganglia of embryonic-day-14 (E14) chicken embryos time-lapse microscopy, Kymograph decrease Positive 219
mannitol 200 mM Neurons derived from the dorsal root ganglia of embryonic-day-14 (E14) chicken embryos time-lapse microscopy, Kymograph decrease Positive 219
Valinomycin 10 μM decrease Positive 217
Antimycin A 100 μM decrease Positive 217
Sodium Azide 25 mM decrease Positive 217
Menadione 10 μM Time lapse fluorescence microscopy decrease Positive 218
H2O2 50 μM Time lapse fluorescence microscopy decrease Positive 218
serotonin 29nM 2h rat Hippocampal Neurons time-lapse imaging experiments increase Positive 215
dopamine 30 nM 2h rat Hippocampal Neurons time-lapse imaging experiments decrease Positive 216
WAY-100635 10nM 2h rat Hippocampal Neurons time-lapse imaging experiments decrease Positive 215
Fluoxetine 3 μM rat Hippocampal Neurons time-lapse imaging experiments increase Positive 215