F0106 | Ionophore
| Compound | Dose | Time | Species | Model | Method | Action | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Valinomycin | affect | Positive | 201 | ||||||
| gramicidin | affect | Positive | 201 | ||||||
| Nigericin | affect | Positive | 201 | ||||||
| monensin | affect | Positive | 201 | ||||||
| dianemycin | affect | Positive | 201 | ||||||
| A23187 | affect | Positive | 201 | ||||||
| ionomycin | affect | Positive | 201 | ||||||
| X-537A | affect | Positive | 201 | ||||||
| ionomycin | rat | liver mitochondria | Efflux of mitochondrial Mg2+ was determined by dual wavelength spectroscopy in the presence of 100 PM Eriochrome Blue SE, an indicating dye for free Mg | affect | Positive | 202 | |||
| A23187 | affect | Positive | 203 | ||||||
| Bafilomycin A1 | male Wistar rats | liver mitochondria | affect | Positive | 199 | ||||
F010601. transport of protons and charge (proton ionophore)
F010602. transport of charge but not protons
F010603. transport of protons but not charge (K+)
F010604. transport of protons but not charge (Na+)
F010605. transport of protons but not charge (Ca2+ or Mg2+)
F010606. transport of protons but not charge (Cations)
F010602. transport of charge but not protons
F010603. transport of protons but not charge (K+)
F010604. transport of protons but not charge (Na+)
F010605. transport of protons but not charge (Ca2+ or Mg2+)
F010606. transport of protons but not charge (Cations)