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The pyrethroids permethrin and cyhalothrin are potent inhibitors of the mitochondrial complex I. |
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Pterulinic acid and pterulone, two novel inhibitors of NADH:ubiquinone oxidoreductase (complex I) produced by a Pterula species. II. Physico-chemical properties and structure elucidation. |
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The Journal of Antibiotics |
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Measurement of the membrane potential generated by complex I in submitochondrial particles |
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Cellular and mitochondrial toxicity of zidovudine (AZT), didanosine (ddI) and zalcitabine (ddC) on cultured human muscle cells. |
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Journal of the Neurological Sciences |
1997 |
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272. |
Glucocorticoids inhibit mitochondrial matrix acyl-CoA dehydrogenases and fatty acid beta-oxidation. |
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The American Journal of Physiology |
1997 |
10.1152/ajpgi.1997.272.5.G1141 |
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N-deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes. |
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Toxicology |
1997 |
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146. |
Inhibition of succinic dehydrogenase and F0F1-ATP synthase by 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid (DIDS). |
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Effects of trimetazidine on the calcium transport and oxidative phosphorylation of isolated rat heart mitochondria. |
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Probing the ubiquinone reduction site of mitochondrial complex I using novel cationic inhibitors. |
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The Journal of Biological Chemistry |
1997 |
10.1074/jbc.272.26.16176 |
125. |
Quinolones and their N-oxides as inhibitors of mitochondrial complexes I and III |
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Biochimica et Biophysica Acta (BBA) - Bioenergetics |
1997 |
10.1016/S0005-2728(96)00150-8 |
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Effect of dopamine, dimethoxyphenylethylamine, papaverine, and related compounds on mitochondrial respiration and complex I activity. |
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1996 |
10.1046/j.1471-4159.1996.66031174.x |
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Ranolazine increases active pyruvate dehydrogenase in perfused normoxic rat hearts: evidence for an indirect mechanism. |
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1996 |
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Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone. |
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Biochemical Pharmacology |
1996 |
10.1016/0006-2952(96)00204-3 |
51. |
Pentamidine is an uncoupler of oxidative phosphorylation in rat liver mitochondria. |
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Archives of Biochemistry and Biophysics |
1996 |
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106. |
The specificity of mitochondrial complex I for ubiquinones. |
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The Biochemical Journal |
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Nonsteroidal antiinflammatory drugs and uncoupling of mitochondrial oxidative phosphorylation. |
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Arthritis and Rheumatism |
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Comparison of the inhibitory action of synthetic capsaicin analogues with various NADH-ubiquinone oxidoreductases |
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Biochimica et Biophysica Acta (BBA) - Bioenergetics |
1996 |
10.1016/0005-2728(95)00131-X |
112. |
Thienylimidazo[2,1-b]thiazoles as inhibitors of mitochondrial NADH dehydrogenase. |
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Journal of Medicinal Chemistry |
1995 |
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Evidence for three separate electron flow pathways through complex I: an inhibitor study |
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Biochimica et Biophysica Acta (BBA) - Bioenergetics |
1995 |
10.1016/0005-2728(95)94411-Q |
79. |
Characterization of the excitotoxic potential of the reversible succinate dehydrogenase inhibitor malonate. |
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Journal of Neurochemistry |
1995 |
10.1046/j.1471-4159.1995.64010430.x |
67. |
On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide. |
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Toxicology |
1995 |
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122. |
The antianginal agent ranolazine is a weak inhibitor of the respiratory complex I, but with greater potency in broken or uncoupled than in coupled mitochondria. |
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Biochemical Pharmacology |
1995 |
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319. |
1-Chloro-2,4-dinitrobenzene is an irreversible inhibitor of human thioredoxin reductase. Loss of thioredoxin disulfide reductase activity is accompanied by a large increase in NADPH oxidase activity. |
Arn?r, E S; Bj?rnstedt, M; Holmgren, A |
The Journal of Biological Chemistry |
1995 |
10.1074/jbc.270.8.3479 |
109. |
New inhibitors of complex I of the mitochondrial electron transport chain with activity as pesticides. |
Hollingworth, R M; Ahammadsahib, K I; Gadelhak, G; McLaughlin, J L |
Biochemical Society Transactions |
1994 |
10.1042/bst0220230 |
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Two binding sites of inhibitors in NADH: ubiquinone oxidoreductase (complex I). Relationship of one site with the ubiquinone-binding site of bacterial glucose:ubiquinone oxidoreductase. |
Friedrich, T; van Heek, P; Leif, H; Ohnishi, T; Forche, E; Kunze, B; Jansen, R; Trowitzsch-Kienast, W; Höfle, G; Reichenbach, H |
European Journal of Biochemistry / FEBS |
1994 |
10.1111/j.1432-1033.1994.tb19985.x |
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Flunarizine and cinnarizine inhibit mitochondrial complexes I and II: possible implication for parkinsonism. |
Veitch, K; Hue, L |
Molecular Pharmacology |
1994 |
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Characterization of the inhibitory mechanism of 1-methyl-4-phenylpyridinium and 4-phenylpyridine analogs in inner membrane preparations. |
Gluck, M R; Krueger, M J; Ramsay, R R; Sablin, S O; Singer, T P; Nicklas, W J |
The Journal of Biological Chemistry |
1994 |
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Inhibition by perhexiline of oxidative phosphorylation and the beta-oxidation of fatty acids: possible role in pseudoalcoholic liver lesions. |
Deschamps, D; DeBeco, V; Fisch, C; Fromenty, B; Guillouzo, A; Pessayre, D |
Hepatology |
1994 |
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Aminoethylcysteine ketimine decarboxylated dimer inhibits mitochondrial respiration by impairing electron transport at complex I level. |
Pecci, L; Montefoschi, G; Fontana, M; Cavallini, D |
Biochemical and Biophysical Research Communications |
1994 |
10.1006/bbrc.1994.1293 |