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168. Identification of small molecule inhibitors of human cytochrome c oxidase that target chemoresistant glioma cells. Oliva, Claudia R; Markert, Tahireh; Ross, Larry J; White, E Lucile; Rasmussen, Lynn; Zhang, Wei; Everts, Maaike; Moellering, Douglas R; Bailey, Shannon M; Suto, Mark J; Griguer, Corinne E The Journal of Biological Chemistry 2016 10.1074/jbc.M116.749978
70. A possible site of superoxide generation in the complex I segment of rat heart mitochondria. Ohnishi, S Tsuyoshi; Ohnishi, Tomoko; Muranaka, Shikibu; Fujita, Hirofumi; Kimura, Hiroko; Uemura, Koichi; Yoshida, Ken-ichi; Utsumi, Kozo Journal of Bioenergetics and Biomembranes 2005 10.1007/s10863-005-4117-y
144. F0F1-ATPase of Vibrio parahaemolyticus: purification using new detergents and characterization. Ogawa, W; Izawa, S; Sakai-Tomita, Y; Moritani, C; Tsuda, M; Kinomura, K; Kitazawa, S; Tsuchiya, T Biochimica et Biophysica Acta 1994 10.1016/0005-2728(94)90023-x
124. The acridones, new inhibitors of mitochondrial NADH: ubiquinone oxidoreductase (complex I) Oettmeier, Walter; Masson, Klaus; Soll, Michael Biochimica et Biophysica Acta (BBA) - Bioenergetics 1992 10.1016/0005-2728(92)90036-2
316. Gentamicin affects the bioenergetics of isolated mitochondria and collapses the mitochondrial membrane potential in cochlear sensory hair cells. O'Reilly, Molly; Young, Luke; Kirkwood, Nerissa K; Richardson, Guy P; Kros, Corn? J; Moore, Anthony L Frontiers in Cellular Neuroscience 2019 10.3389/fncel.2019.00416
257. The CPT1a inhibitor, etomoxir induces severe oxidative stress at commonly used concentrations. O'Connor, Roddy S; Guo, Lili; Ghassemi, Saba; Snyder, Nathaniel W; Worth, Andrew J; Weng, Liwei; Kam, Yoonseok; Philipson, Benjamin; Trefely, Sophie; Nunez-Cruz, Selene; Blair, Ian A; June, Carl H; Milone, Michael C Scientific Reports 1905 10.1038/s41598-018-24676-6
164. 5-Fluorouracil induces apoptosis in human colon cancer cell lines with modulation of Bcl-2 family proteins. Nita, M E; Nagawa, H; Tominaga, O; Tsuno, N; Fujii, S; Sasaki, S; Fu, C G; Takenoue, T; Tsuruo, T; Muto, T British Journal of Cancer 1998 10.1038/bjc.1998.617
114. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Nicklas, W J; Vyas, I; Heikkila, R E Life Sciences 1985 10.1016/0024-3205(85)90146-8
201. Bioenergetics Nicholls, David 1905
223. Development of an in silico profiler for mitochondrial toxicity Nelms, Mark D; Mellor, Claire L; Cronin, Mark T D; Madden, Judith C; Enoch, Steven J Chemical Research in Toxicology 2015 10.1021/acs.chemrestox.5b00275
204. The development of structure-activity relationships for mitochondrial dysfunction: uncoupling of oxidative phosphorylation. Naven, Russell T; Swiss, Rachel; Klug-McLeod, Jacquelyn; Will, Yvonne; Greene, Nigel Toxicological Sciences 2013 10.1093/toxsci/kfs279
77. Mode of action of novel acaricide pyflubumide: Effects on the mitochondrial respiratory chain Nakano, Motofumi; Yasokawa, Noriaki; Suwa, Akiyuki; Fujioka, Shinsuke; Furuya, Takashi; Sakata, Kazuyuki Journal of pesticide science 1905 10.1584/jpestics.D14-086
282. Oxazolidinones inhibit cellular proliferation via inhibition of mitochondrial protein synthesis. Nagiec, Eva E; Wu, Luping; Swaney, Steve M; Chosay, John G; Ross, Daniel E; Brieland, Joan K; Leach, Karen L Antimicrobial Agents and Chemotherapy 2005 10.1128/AAC.49.9.3896-3902.2005
177. Current concepts in drug-induced mitochondrial toxicity. Nadanaciva, Sashi; Will, Yvonne Current protocols in toxicology / editorial board, Mahin D. Maines (editor-in-chief) ... [et al.] 2009 10.1002/0471140856.tx0215s40
7. Assessment of drug-induced mitochondrial dysfunction via altered cellular respiration and acidification measured in a 96-well platform. Nadanaciva, Sashi; Rana, Payal; Beeson, Gyda C; Chen, Denise; Ferrick, David A; Beeson, Craig C; Will, Yvonne Journal of Bioenergetics and Biomembranes 2012 10.1007/s10863-012-9446-z
3. Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays. Nadanaciva, Sashi; Bernal, Autumn; Aggeler, Robert; Capaldi, Roderick; Will, Yvonne Toxicology in Vitro 2007 10.1016/j.tiv.2007.01.011
40. Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes. Nadanaciva, Sashi; Aleo, Michael D; Strock, Christopher J; Stedman, Donald B; Wang, Huijun; Will, Yvonne Toxicology and Applied Pharmacology 2013 10.1016/j.taap.2013.06.019
266. Mechanistic target of rapamycin inhibitors: successes and challenges as cancer therapeutics N? Bhaoighill, Muireann; Dunlop, Elaine A. Cancer Drug Resistance 1905 10.20517/cdr.2019.87
248. Mitochondria as a therapeutic target for common pathologies. Murphy, Michael P; Hartley, Richard C Nature Reviews. Drug Discovery 1905 10.1038/nrd.2018.174
30. Effect of dopamine, dimethoxyphenylethylamine, papaverine, and related compounds on mitochondrial respiration and complex I activity. Morikawa, N; Nakagawa-Hattori, Y; Mizuno, Y Journal of Neurochemistry 1996 10.1046/j.1471-4159.1996.66031174.x
207. Inhibition and uncoupling of oxidative phosphorylation by nonsteroidal anti-inflammatory drugs Moreno-S?nchez, Rafael; Bravo, Concepci?n; V?squez, C?sar; Ayala, Guadalupe; Silveira, Luis H; Mart1nez-Lav1n, Manuel Biochemical Pharmacology 1999 10.1016/S0006-2952(98)00330-X
51. Pentamidine is an uncoupler of oxidative phosphorylation in rat liver mitochondria. Moreno, S N Archives of Biochemistry and Biophysics 1996 10.1006/abbi.1996.0041
233. A novel regulatory mechanism of the mitochondrial Ca2+ uniporter revealed by the p38 mitogen-activated protein kinase inhibitor SB202190. Montero, Mayte; Lobaton, Carmen D; Moreno, Alfredo; Alvarez, Javier The FASEB Journal 2002 10.1096/fj.02-0553fje
234. Direct activation of the mitochondrial calcium uniporter by natural plant flavonoids. Montero, Mayte; Lobat?n, Carmen D; Hern?ndez-Sanmiguel, Esther; Santodomingo, Jaime; Vay, Laura; Moreno, Alfredo; Alvarez, Javier The Biochemical Journal 1905 10.1042/BJ20040990
76. Polymyxin B identified as an inhibitor of alternative NADH dehydrogenase and malate: quinone oxidoreductase from the Gram-positive bacterium Mycobacterium smegmatis. Mogi, Tatsushi; Murase, Yoshiro; Mori, Mihoko; Shiomi, Kazuro; Omura, Satoshi; Paranagama, Madhavi P; Kita, Kiyoshi Journal of Biochemistry 2009 10.1093/jb/mvp096
23. Differential effects of typical and atypical neuroleptics on mitochondrial function in vitro. Modica-Napolitano, Josephine S; Lagace, Christopher J; Brennan, William A; Aprille, June R Archives of Pharmacal Research 2003 10.1007/bf02980205
116. Probing the ubiquinone reduction site of mitochondrial complex I using novel cationic inhibitors. Miyoshi, H; Inoue, M; Okamoto, S; Ohshima, M; Sakamoto, K; Iwamura, H The Journal of Biological Chemistry 1997 10.1074/jbc.272.26.16176
261. Restoring mitochondrial superoxide levels with elamipretide (MTP-131) protects db/db mice against progression of diabetic kidney disease. Miyamoto, Satoshi; Zhang, Guanshi; Hall, David; Oates, Peter J; Maity, Soumya; Madesh, Muniswamy; Han, Xianlin; Sharma, Kumar The Journal of Biological Chemistry 2020 10.1074/jbc.RA119.011110
192. Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase). Miyadera, Hiroko; Shiomi, Kazuro; Ui, Hideaki; Yamaguchi, Yuichi; Masuma, Rokuro; Tomoda, Hiroshi; Miyoshi, Hideto; Osanai, Arihiro; Kita, Kiyoshi; Omura, Satoshi Proceedings of the National Academy of Sciences of the United States of America 2003 10.1073/pnas.0237315100
295. Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism. Miret-Casals, Laia; Sebasti?n, David; Brea, Jos?; Rico-Leo, Eva M; Palac?n, Manuel; Fern?ndez-Salguero, Pedro M; Loza, M Isabel; Albericio, Fernando; Zorzano, Antonio Cell Chemical Biology 1905 10.1016/j.chembiol.2017.12.001