T004012 Source: Uniprot
enzyme structureQo site (Qp site or ubiquinol oxidation site)
(Qo site (Qp site or ubiquinol oxidation site))
Quinol--cytochrome-c reductase >>
| Full Name | Qo site (Qp site or ubiquinol oxidation site) |
|---|
| Compound | Dose | Time | Species | Model | Method | Result | Positive criterion | Reference |
|---|---|---|---|---|---|---|---|---|
| hhdbt uhnq | 100 mM | incubated overnight | bovine | isolated heart mitochondria | Measurements of redox potentials of the ISP | Positive | 83 | |
| dibromothymoquinone | 100 mM | incubated overnight | bovine | isolated heart mitochondria | Measurements of redox potentials of the ISP | Positive | 83 | |
| atorvastatin | C2C12 myoblasts | Positive | 180 | |||||
| NQNO | bovine | isolated heart mitochondria cytochrome bc1 complex | Positive | 166 | ||||
| Simvastatin | 200uM | bovine | heart mitochondria | Reduction of the CIII cytochromes c1 and b was determined spectrophotometrically in bovine heart mitochondria. | Positive | p < 0.01 | 180 | |
| Myxothiazol | Positive | 81 | ||||||
| moas | Positive | 82 | ||||||
| azoxystrobin | Positive | 83 | ||||||
| oudemansin a | Positive | 84 | ||||||
| strobilurin a | Positive | 84 | ||||||
| cpmb-oxime | Positive | 84 | ||||||
| azoxystrobin | 100 mM | incubated overnight | bovine | isolated heart mitochondria | Measurements of redox potentials of the ISP | Positive | 83 | |
| famoxadone | 100 mM | incubated overnight | bovine | isolated heart mitochondria | Measurements of redox potentials of the ISP | Positive | 83 | |
| stigmatellin | 100 mM | incubated overnight | bovine | isolated heart mitochondria | Measurements of redox potentials of the ISP | Positive | 83 | |
| uhdbt | 100 mM | incubated overnight | bovine | isolated heart mitochondria | Measurements of redox potentials of the ISP | Positive | 83 | |